Research in DNA computing and molecular programming draws together mathematics, computer science, physics, chemistry, biology, and nanotechnology to address the analysis, design, and synthesis of information-based molecular systems. This annual meeting is the premiere forum where scientists with diverse backgrounds come together with the common purpose of using interdisciplinary approaches to advance molecular computation. Continuing this tradition, the 23rd International Conference on DNA Computing and Molecular Programming (DNA23), under the auspices of the International Society for Nanoscale Science, Computation and Engineering (ISNSCE), will focus on the most recent experimental and theoretical results that promise the greatest impact. In addition, this conference will have special sessions on how to advance nanotechnology education, and how learning about DNA computing can provide students with deeper insights in multiple disciplines.