We are pleased to extend an invitation for your contributions to our dedicated Research Topic, "Single Cell RNA Expression in Pancreatic Cancer," presented by Frontiers in Genetics.

The complexity and heterogeneity of pancreatic cancer have long been acknowledged in the medical community. With the advent of advanced single cell technologies, we now possess the unprecedented ability to dissect and analyze gene expression alterations within individual tumor cells and their microenvironments. Such insights are imperative to comprehend the multifaceted impacts of gene expression variations on disease development, progression, and therapeutic response.

Our objective with this Research Topic is to assemble a comprehensive overview of the current state of knowledge in the field of single cell RNA expression in pancreatic cancer. We welcome contributions that encompass both systematic reviews and novel research findings. The scope of this topic includes, but is not limited to, the following areas:

In-depth analyses through single cell RNA sequencing in pancreatic cancer.
Explorations of spatial transcriptomics within this context.
Comparative studies of gene expression in tumor microenvironments versus cancer cells.
Innovations in scATAC-seq applications for pancreatic cancer.
Investigations into the evolution of single cell gene expression across disease progression and in response to treatments.
This Research Topic presents a significant platform for sharing groundbreaking research, fostering collaboration among peers, and contributing to a nuanced understanding of pancreatic cancer at the single-cell level.

We eagerly anticipate your valuable contributions and insights. Together, let us advance the frontiers of knowledge in pancreatic cancer research.

The Editorial Team

Co-editors: Rick Jansen, Elena Grassi, and Roberta Bardini
Content specialists: Trinity King and Emily Arnold.